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Beeken BioMedical LLC (Raleigh) develops and commercializes hemostasis wound dressings and polymer-based liquid bandage products. BENANOVA Inc. (Raleigh) develops antimicrobial nanotechnology products for the disinfectant, cosmetic and agricultural industries. Benson Hill Biosystems Inc. (Research Triangle Park) is an agricultural biotechnology company focused on the development of traits to increase crop yield. Bent Creek Institute Inc. (Asheville) conserves and develops plant biodiversity assets and maintains the North Carolina Arboretum's Bent Creek Germplasm Repository. It also administers the U.S. Botanical Safety Laboratory, a consortium of university botanical research sites. Bespoke Therapeutics LLC ( Winston- Salem) is using virus-like-particle (VLP) technology and protein therapy to develop a vaccine for the treatment of breast cancer. BestCo Inc. (Mooresville) manufactures confectionery-based dosage forms for nonprescription drug products and dietary supplements. BHV Pharma Inc. (Research Triangle Park) develops therapeutics for metabolic disorders, including Type 2 diabetes and liver disease (NAFLD/NASH). Bio Products Laboratory USA Inc. (Durham) manufactures and distributes plasma-derived products, including intravenous immunoglobin preparations, coagulation factors and albumin solution. The Durham of ce is the U.S. distributor for BPL products. BioAgilytix Labs Inc. (Durham) is a bioanalytical lab specializing in large-molecule bioanalysis, of ering PK, immunogenicity, biomarkers and cell-based assays in support of the development and release testing of biologics and small-molecule therapeutics. BIoCI Systems Inc. (Raleigh) provides sterilization validation services and other contract laboratory testing services. Biocomposites Inc. (Wilmington) develops, manufactures and distributes synthetic tissue regeneration products. The Wilmington of ce is a sales of ce. BioCryst Pharmaceuticals Inc. (Durham) designs and develops small-molecule pharmaceuticals that block key enzymes involved in infectious diseases, inf ammatory diseases and cancer. BioCytics Inc. (Huntersville) of ers circulating tumor cell isolation, enumeration and analysis services for oncology drug development and research. They also have an ongoing IRB- approved clinical trial for the collection of blood and tissue samples from cancer patients. BioDelivery Sciences International Inc. (Raleigh) is a specialty pharmaceutical company with a focus in the areas of pain management and addiction. More than 61,000 North Carolinians work in the life sciences statewide, earning an average salary of $81,000 a year – about twice that of overall private sector earnings in the state. Companies Be – Bi North Carolina Bioscience Companies 6 ALAMANCE REGIONAL MEDICAL CENTER

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