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108Labs LLC (Research Triangle Park) uses cell-based synthesis to produce textile, food and building commodities. 13C Molecular Inc. (Fayetteville) provides stable-isotope labeled and native compounds to the pharmaceutical and biomedical industries via custom organic synthesis and sourcing through a consortium of manufacturers. 4D Biotech Inc. (Raleigh) develops biological microarray instrumentation. AAIPharma Services Corp. (Wilmington and Durham) provides contract drug development and manufacturing services, including formulation development, analytical chemistry and solid dose and parenteral drug manufacturing for both clinical and commercial markets. AbD Serotec, a Bio-Rad Company (Raleigh) designs, manufactures and sells immunological and cell biology reagents for research, and provides antibody services. Accord Healthcare Inc. (Durham) develops and manufactures generic pharmaceuticals. Their portfolio includes therapeutics in oncology, cardiology, neurology, nephrology, urology, psychiatry, diabetes and pain management. The North Carolina location is a sales of ce. AccuGenomics Inc. (Wilmington) develops gene expression tests to diagnose and monitor cancer treatment. Achelios Therapeutics Inc. (Chapel Hill) develops therapeutics for the treatment of migraine and peripheral pain. ACRIS Pharmaceuticals LLC (Chapel Hill) develops and commercializes unique early stage compounds. Adhezion Biomedical LLC (Hudson) develops and produces cyanoacrylate-based medical adhesive, wound care and microbial barrier products for connective tissue (human skin). The company's manufacturing and research facility is located in Hudson, N.C. Adroit Pharmaceutical Development LLC (Durham) identif es new and improved formulations and process technologies. Its primary focus is on inhalation and dermatological product development. Advanced Animal Diagnostics Inc. (Durham) develops and commercializes diagnostics to detect and manage disease states, reproductive, nutritional and overall health status of production animals. AAD's f rst product is a diagnostic test for mastitis in dairy cows. Advanced Laboratories Inc. (Clayton) provides chemical and microbiological analysis of dietary supplements and food products. Advanced Tear Diagnostics LLC (Raleigh) develops and markets a point-of-care lab testing system designed to assist eye care physicians in detecting and quantifying biomarkers associated with external ocular disorders. Aegis Women's Health Technologies Inc. (Raleigh) develops medical devices to help reduce recurrent urinary tract infections in women. Aerial Biopharma LLC (Morrisville) develops biologic and small-molecule central nervous system therapeutics, including treatments for narcolepsy. Aerie Pharmaceuticals Inc. (Research Triangle Park) discovers, develops and commercializes f rst-in-class therapies for the treatment of patients with glaucoma. Aerocrine Inc. USA (Morrisville) designs and develops products to aid in the diagnosis and control of respiratory disease. Af nergy LLC (Durham) uses biotechnology methods to create application-specif c coatings for orthopedic and cardiovascular medical devices. Af nergy discovers peptides that can capture, deliver and retain specif c proteins, drugs or cells. AgBiome Inc. (Research Triangle Park) conducts discovery and early-stage research using the crop microbiome to identify products that reduce risk and improve yields. Agile EndoSurgery Inc. (Research Triangle Park) develops endoscopic surgical devices. Agile Sciences Inc. (Raleigh) has identif ed small molecules that inhibit and disperse bacterial biof lms. The company is investigating applications in medicine, agriculture and industry. Ajinomoto North America (Raleigh) manufactures pharmaceutical-grade amino acids and custom-blended amino acid mixtures. Alderon BioSciences Inc. (Beaufort) develops point-of-care diagnostics. Alera Labs LLC (Research Triangle Park) provides contract research analytical chemistry, in vitro toxicology, GLP analysis and preformulation services to pharmaceutical, biotech and medical device companies. Algaen Corp. (Winston-Salem) is exploring microalgae to develop, produce and market products and technologies for the nutraceutical, pharmaceutical and bio-energy industries. Algynomics Inc. (Chapel Hill) uses phenotyping and genomics to develop diagnostics and therapeutics for chronic pain and related conditions. Companies 1 – An North Carolina Bioscience Companies 2

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