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Entera Health Inc. (Cary) develops biotherapeutic products for enteropathy. Enteric Solutions Corp. (New Bern) develops innovative pharmaceutical technologies for the treatment of enteric disease in developing countries. ENTEX Technologies Inc. (Chapel Hill) provides advanced biological and f ltration wastewater treatment that can be customized for various industries. EntoGenetics Inc. (Charlotte) engineers the production of spider silk at a commercial scale through the genetic transformation of silkworms. Spider silk is a very strong f ber that has applications in the biomedical, defense and textile industries. ENVIGEN Pharmaceuticals Inc. (Durham) develops classes of new small drug-like molecules to treat life-threatening diseases including cancer, HIV/AIDS and neurological disorders. Environmental Testing Solutions Inc. (Asheville) of ers microbiological and chemical testing for drinking water and wastewater, and aquatic biomonitoring toxicity testing. Envisia Therapeutics Inc. (Morrisville) works to discover and develop novel therapies to address signif cant unmet medical needs in ophthalmology. Enzerna Biosciences LLC (Chapel Hill) creates sequence-specif c RNA processing enzymes capable of modulating RNA expression without permanent alteration of the target gene. These tools will enable precise manipulation of expression for any target of choice. eosMYCO Inc. (Charlotte) provides environmental remediation services and is specif cally focused on rehabilitation of terrestrial sites of chemical and metallic contaminants using mycological biotechnology applications. EpiCypher Inc. (Research Triangle Park) develops and manufactures novel products and tools for epigenetics and chromatin biology research. The company also provides services to discovery groups in industry and academia. EPL Inc. (Durham) provides GLP-compliant toxicologic pathology and related services including necropsy, histology, immunohistochemistry, pathology evaluation, EM, stereology, pathology peer reviews, specimen storage and consultation. Eppin Pharma Inc. (Chapel Hill) is developing a nonhormonal male oral contraceptive. Eton Bioscience Inc. (Research Triangle Park) specializes in DNA sequencing and of ers other services such as gene and peptide synthesis, mutagenesis and mammalian cell expression. Eurof ns Agroscience Services Inc. (Mebane) provides contract research services, product development consulting and technical support to the crop protection, agricultural biotechnology and pest control industries. www.eurof aspx Exela Pharma Sciences LLC (Lenoir) develops and manufactures injectable, ophthalmic and inhalation pharmaceuticals. The Lenoir site is a sterile manufacturing facility, compliant with cGMP and other FDA regulations. Exodos Life Science Partners (Chapel Hill) is a semi-virtual pharmaceutical development company advancing product concepts through the 505(b)(2) process to early clinical proof-of-principle and sale. Expression Analysis Inc., a Quintiles company (Durham) provides gene expression and genotyping assays, DNA sequencing services, sequence enrichment technologies, marker-assisted breeding and bioinformatics support. The lab is CLIA-registered. f(x) Immune Inc. (Candler) provides advanced testing services to developers of immuno- therapeutics and vaccines using its proprietary technologies. The company's product development pipeline includes related clinical diagnostics, POC and companion assays and systems. Fair Products Inc. (Cary) manufactures and distributes tobacco crop care products including insecticides, sucker control, ripeners and fertilizers. Fennec Pharmaceuticals Inc. (Research Triangle Park) develops cancer therapeutics. Its lead product under development is Eniluracil, an oral dihydropyrimidine dehydrogenase inhibitor to improve the tolerability and ef ectiveness of oncology drugs. Fervent Pharmaceuticals LLC (Greenville) develops a nonhormonal product, FP-101, to treat vasomotor symptoms associated with menopause. FHI 360 (Durham) develops responses to HIV/ AIDS and other health and nutrition concerns in resource-poor settings. The laboratory in Durham of ers medical-device and pharmaceutical testing services. First Flight Biosciences Inc. (Morrisville) provides contract drug discovery research services, including lead optimization in preclinical drug discovery, assay development, compound prof ling, high-throughput screening, in vivo pharmacology, DMPK and bioanalytics. www.f rstf FLAG Therapeutics Inc. (Raleigh) develops cancer therapeutics using new classes of small molecules which have selective dual activity: antiangiogenesis and chemotherapeutic. www.f Life science companies make good neighbors: clean, quiet, their employees are smart and they pay about $1.8 billion a year in state & local taxes. Companies En – Ge North Carolina Bioscience Companies 16

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