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Companies 1 – Ae 13C Molecular Inc. (Fayetteville) provides stable-isotope labeled, custom synthesized organic compounds to the pharmaceutical and biomedical industries. AAIPharma Services Corp. (Wilmington and Durham) provides drug product development services such as formulation development, analytical chemistry and manufacturing. The company's solid-dose manufacturing facility provides clinical and commercial supplies on contract. AccuGenomics Inc. (Wilmington) develops gene expression tests to diagnose and monitor cancer treatment. Ace Bio-PharmTech LLC (High Point) uses asymmetric synthesis technologies to develop R&D processes, formulations of branded and generic pharmaceuticals, and active pharmaceutical ingredients. Achelios Therapeutics Inc. (Chapel Hill) develops therapeutics for the treatment of migraine and peripheral pain. Actavis U.S. (Lincolnton) manufactures OTC and prescription hydrocortisone, anti-fungal and permethrin products as creams, ointments, liquids and suppositories. Adherex Technologies Inc. (Research Triangle Park) develops cancer therapeutics. Its lead product under development is Eniluracil, an oral dihydropyrimidine dehydrogenase inhibitor to improve the tolerability and efectiveness of oncology drugs. Adhezion Biomedical LLC (Hudson) develops and produces cyanoacrylate-based medical adhesive, wound care and microbial barrier products for connective tissue (human skin). Adroit Pharmaceutical Development LLC (Durham) identifes new and improved formulations and process technologies. Its primary focus is on inhalation and dermatological product development. ADS Pharma Consulting LLC (Apex) provides drug development services, including active pharmaceutical ingredient route development and manufacturing, analytical, pre- and formulation development, clinical batch manufacture and CMC regulatory afairs. Advanced Animal Diagnostics Inc. (Durham) develops and commercializes diagnostics to detect and manage disease states, reproductive, nutritional and overall health status of production animals. AAD's frst product is a diagnostic test for mastitis in dairy cows. Advanced Liquid Logic Inc. (Morrisville) uses digital microfuidics to develop molecular diagnostics, bioassays and life-science research tools. Advanced Tear Diagnostics LLC (Raleigh) develops and markets a point-of-care lab testing system designed to assist eye-care physicians in detecting and quantifying biomarkers associated with external ocular disorders. Aegis Women's Health Technologies Inc. (Raleigh) develops medical devices to help reduce recurrent urinary tract infections in women. Aerial Biopharma LLC (Morrisville) develops biologic and small-molecule central nervous system therapeutics, including treatments for narcolepsy and chronic pain. Aerie Pharmaceuticals Inc. (Research Triangle Park) researches and develops treatments for glaucoma. NCSU Aerocrine Inc. USA (Morrisville) designs and develops products to aid in diagnosis and control of respiratory disease. 2 North Carolina Companies

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