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Companies Gr – Hu Grifols Inc. (Research Triangle Park, Raleigh and Clayton) develops and produces medical treatments using blood or blood components for people with life-threatening disorders in a variety of therapeutic areas including immunology, pulmonology and hemostasis. Grifols' Clayton plant is the company's primary manufacturing facility, producing proteins to treat rare diseases, including immune defciencies and genetic emphysema. GTCAllison LLC (Mocksville) researches and develops diagnostic tests for animal pathogens. Happy Jack Inc. (Snow Hill) manufactures insecticides and pharmaceutical preparations to treat dogs. HCEC LLC (Winston-Salem) isolates cells from donor corneas to grow replacement corneal tissue in the laboratory. HDH Pharma Inc. (Morrisville) provides contract chemistry research services to pharmaceutical and biotechnology companies, including medicinal and process chemistry and custom synthesis. Health Decisions Inc. (Durham) is a global clinical research organization that specializes in applying adaptive principles to both trial design and operations. Heat Biologics Inc. (Chapel Hill) develops therapeutic vaccines to combat a range of cancers and infectious diseases. Helical Sciences Inc. (Greensboro) develops a rapid, polymerase chain reaction-based microbiological diagnostic product, with potential applications in water, food and beverage. Hemo Bioscience Inc. (Research Triangle Park) is an FDA-registered manufacturer of blood-typing reagents and diagnostics for the blood-banking industry. Hemodynamic Therapeutics (Durham) develops small-molecule combination therapy for obesity-related hypertension. HepatoSys Inc. (Cornelius) develops technologies for functional restoration of donor livers for use in transplantation and production of hepatocytes for research. High Point Clinical Trials Center (High Point) conducts Phase I and II clinical research studies for pharmaceutical companies. High Point Pharmaceuticals LLC (High Point) was spun out of TransTech Pharma to manage the development of drugs for obesity and diabetes. HOMS LLC (Pittsboro) develops, manufactures and markets natural products such as the Bite Blocker line of insect repellents and Bio Block organic insecticides. Hongene Biotechnology USA Inc. (Morrisville) develops and manufactures bio-reagents such as nucleosides, nucleotides and phosphoramidite products. Hospira Inc. (Rocky Mount and Clayton) manufactures injectable hospital products at its facility in Rocky Mount. The facility also provides contract manufacturing services such as aseptic flling, lyophilization, terminal sterilization and more. Hospira's Clayton plant makes generic acute injectable drugs for intravenous use. The Clayton facility also provides contract manufacturing services. Howard Associates LLC (Research Triangle Park) provides preclinical contract research services to the pharmaceutical industry. The company uses rodent models to predict the efcacy of experimental compounds, especially for CNS diseases, and to predict CNS side efects. UNC-G HRF Inc. (Raleigh) is a plasma center that provides human blood plasmas for bioscience research. 16 North Carolina Companies Humacyte Inc. (Morrisville) develops processes to engineer human tissue scafolds that can be shaped into tubes, sheets or particulates for regenerative medicine uses. The current product focus includes vascular disease, therapeutic flling and soft-tissue repair.

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