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Companies Ch – Co Chelsea Therapeutics International Ltd. (Charlotte) acquires and develops products for the treatment of various human diseases including central nervous system, rheumatoid arthritis, psoriasis and other infammatory conditions. Chem-Tex Laboratories Inc. (Concord) develops and manufactures specialty chemicals for the textile, paper and industrial polymer industries. One product, called Bac-Shield, contains a natural microbial extracted from snow crab shells. Chematron Inc. (Charlotte) manufactures textile chemicals and has the capability for contractual custom manufacture of specialty chemicals. Chemtura USA (Gastonia) manufactures specialty chemicals and crop protection products. Chem-Bac Laboratories Inc. (Charlotte) is an FDA-registered analytical testing laboratory. ChemoGenics Biopharma LLC (Research Triangle Park) provides drug discovery research services such as medicinal chemistry, DMPK, bioinformatics and preclinical models in cancer, infammation and metabolic diseases. ChemQ Bioscience LLC (Research Triangle Park) develops new and cost-efective in vitro clinical diagnostics known as liquid base cytology products for the screening of cancer cells. Chesson Laboratory Associates Inc. (Durham) develops polymer-based medical products. Chiltern International Inc. (Wilmington) conducts Phase I through IV global clinical trials across a broad range of therapeutic areas, functional service provision and contract stafng solutions. Chimerix Inc. (Durham) develops oral antiviral therapeutics for viral diseases including adenoviruses, CMV, BK virus, HPV, HIV and HCV. Chirazyme Labs Inc. (Greenville) produces enzymes for stereospecifc epoxidation intermediates in pharmaceutical synthesis. Cirrus Pharmaceuticals Inc. (Durham) provides product development services, including physical and chemical characterization, formulation development, stability testing, process development as well as scale-up and technical transfer to manufacturing. CivaTech Corp. (Raleigh) develops materials for radiation therapy, including stent applications. CivaTech Oncology Inc. (Research Triangle Park) develops radioactive polymer-based devices to treat localized tumors. CiVentiChem (Cary) provides contract R&D services, medicinal chemistry, lead optimization, process R&D, cGMP synthesis of APIs for clinical trials, cGMP/GLP analytical services, CMC consulting and custom synthesis of pharmaceutical intermediates and APIs. Clearside Biomedical Inc. (Research Triangle Park) develops and commercializes ophthalmic therapeutic products that use an ocular microinjection platform to target individual compartments of the eye. Clinical Sensors Inc. (Chapel Hill) develops diagnostic tests and nitric oxide sensors for the early detection of sepsis. Cmed Clinical Services (Durham) provides clinical services to drug development organizations and manages early-phase studies (Phase I - IIb) with a focus in oncology, infectious disease, respiratory and cardiology. AVocA Cognosci Inc. (Research Triangle Park) develops neurorestorative therapies for Alzheimer's disease, multiple sclerosis, traumatic brain injury, nerve crush and other disease and trauma indications. 10 North Carolina Companies

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